Oncotype DX Colon Cancer Treatment Decision

In this video, Dr. Kozloff explains how the Oncotype DX test can be used to treat colon cancer patients. He describes that the test helps out greatly with prognosis, which can help the surgeon decide if chemotherapy is the best option for them.

Mark F. Kozloff, MD: Oncotype DX can help us determine many times of patients with stage 2 patients should or should not get chemotherapy. One takes all patients with stage 2 and do surgery on those patients and then give chemotherapy, we know that those patients have on the whole approximately at 2.5% chance of benefiting from chemotherapy which is a very low benefit of chemotherapy. That one can tell if the person has a more malignant illness or a less malignant illness, if they more likely they have the cancer come back or less likely they have the cancer come back than one can better tell if chemotherapy has a higher or less likely chance of benefiting patients and actually doing Oncotype DX may distinguish between a 2% benefit and a 7% benefit of getting chemotherapy in stage 2. That may be very helpful for both the doctor as well as the patient on making a decision. I think it is important to say that Oncotype DX is very helps us with the prognosis. It doesn’t always predict or is not predictive in telling us of chemotherapy will or not be helpful, but knowing what a person’s prognosis is can help us tell if chemotherapy will be more likely to be helpful or less likely to be helpful.

Mark F. Kozloff, MD, has more than 30 years of experience treating many types of adult cancers. He works on a multidisciplinary team of experts in the Center for Gastrointestinal Oncology where he specializes in the treatment of colorectal malignancies.

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This information should not be relied upon as a substitute for personal medical advice, diagnosis or treatment. Use the information provided on this site solely at your own risk.  If you have any concerns about your health, please consult with a physician.


This information should not be relied upon as a substitute for personal medical advice, diagnosis or treatment. Use the information provided on this site solely at your own risk. If you have any concerns about your health, please consult with a physician.

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